Chrysanthemum. Increase food intake of vitamin C and consider supplementing with 500 mg per day. In ihrer Heimat Ostasien war das schon zu Zeiten des Philosophen und Religionsstifters Konfuzius (551 bis 479 vor Christus) so. Herbst-Chrysanthemen sind die perfekten Hingucker in Eingangsbereichen. Rather, they have a calming effect that is attributable to supposed sedative substances in Apocynum venetum. CF is also very common in traditional Chinese medicine, in which it is used as a heat clearing and detoxification herb. asiatica Pamp., as at http://mpns.kew.org/mpns-portal). A guaianolide sesqui-terpenoids (43) isolated from Chrysanthemum indicum showed NO inhibition with the IC50 value of 1.4 μM. Compound 74 displayed excellent NO inhibition through NF-kB signalling pathway with an IC50 value of 0.36 μM. It also attenuated oxidant enzymes [myeloperoxidase (MPO) and MDA]. Eine Überwinterung der Wurzelstöcke in hellen, frostfreien Räumen lohnt sich meist nicht. Suggested uses. Nearly, 100 compounds displayed comparable or better activity then the standard drug used in that experiment. The plant … Man sucht Herbst-Chrysanthemen eher nach Blütenfarbe als nach Sortenname aus. It is a member of the genus Chrysanthemum, which consists of about 30 species and belongs to the family Asteraceae (Compositae). Individual polyphenols were quantified using LC–ESI-MS/MS on a triple quadrupole. Synonyms include Achillea bandana, Achillea berdana, and Arctotis elegans. It is a member of the genus Chrysanthemum, which consists of about 30 species and belongs to the family Asteraceae (Compositae). Flavonol patterns could be chemotaxonomic descriptors to characterize onion germplasm. Chrysanthemi Flos (CF) is the flower of Chrysanthemum indicum Linne or Chrysanthemum morifolium Ramatuelle [2].It is a member of the genus Chrysanthemum, which consists of about 30 species and belongs to the family Asteraceae (Compositae).These species were previously classified … Leaf, main color Dark green. Moreover, numerous compounds such as Ginko biloba extract 761 (EGb761) and S-Allylcysteine (SAC) can attain a free radical scavenging action to inactivate nitrous oxide (NO) and hydrogen peroxide (H2O2) radicals [34,35]. Anders als die oft langstieligen Garten-Chrysanthemen, auch als Winterastern bekannt, zeichnen sich Chrysanthemum Indicum-Hybriden durch ihren kugeligen Wuchs sowie eine reiche Rundum-Blüte aus. Br., and Codariocalyx motorius (Houtt.) Durch den Feuchtigkeitskreislauf in der gespannten Luft bewurzeln die Stecklinge besser. Decken Sie den Kasten mit Glas oder Plastikfolie ab. Chen ZN, Xu PJ (1987) Structural determination of yejuhua lactone, isolated from Chrysanthemum indicum L. Yao Xue Xue Bao 22(1):67–69 (in Chinese) PubMed Google Scholar. The plant’s native range extends from Eastern China all the way to Central and Southern Japan. An important question is which variety of Cannabis should be made available for medicinal use (Hazekamp and Fischedick, 2012). Join Us. To repel insects – Chrysanthemum flowers have a special weapon – pyrethrum. Recently, there have been efforts in China to develop therapeutic applications of oral formulas containing powder from Apocynum venetum leaves and other medical herbs such as Chrysanthemum indicum L., Stephania tetrandea S. Moore, the combination of which is a promising antihypertensive formula. Sie wird Chinesische Chrysantheme, Japanische Chrysantheme oder Indische Chrysantheme genannt. The predominant components of the essential oils were 1,8-cineole (0.62–7.34%), (+)-(1R,4R)-camphor (0.17–27.56%), caryophyllene oxide (0.54–5.8%), β-phellandrene (0.72–1.87%), (−)-(1S,2R,4S)-borneol acetate (0.33–8.46%), 2-methyl-6-(p-tolyl)hept-2-ene (0.3–8.6%), 4,6,6-trimethylbicyclo[3.1.1]hept-3-en-2-yl acetate (0.17–26.48%), and hexadecanoic acid (0.72–15.97%). Likely, triterpenes isolated from Gymnosporia heterophylla, which displayed COX-2 inhibition comparable to Celecoxib (IC50 0.43 mM) with the IC50 values of 0.46 (82), 0.45 (85) and 0.43 mM (87), respectively. Photo Chrysanthemum (Indicum Grp) Bonbini on Group Flowers. Krysantemum - Chrysanthemum indicum Print med billeder. Flower color distribution: Marginate. Abdelrahman Ibrahim Abushouk, ... Mohamed M. Abdel-Daim, in Biomedicine & Pharmacotherapy, 2017. Decrease consumption of red meat and excessive seafood. Wollen Sie eine Chrysanthemum Indicum-Hybride, die Ihnen besonders gut gefällt, doch überwintern, schlagen Sie die Wurzelstöcke in einer Kiste mit frischer Erde ein, um sie im nächsten Frühjahr zu teilen oder Stecklinge zu nehmen (siehe Vermehrung). Wenyan Xie, ... Jianjun Hu, in Journal of Ethnopharmacology, 2012. In this review, we summarize current knowledge about the anti-inflammatory activity of luteolin from in vitro, in vivo, and in silico studies published since 2009. In addition to their many pharmacological benefits, luteolin and its derivatives are relatively tolerable to various cell types. Die einfach blühende Herbst-Chrysanthemen-Sorte 'L'Innocence‘ gehört dank ihrer Winterhärte zu den letzten Schnittblumen im Garten. Je nachdem, aus welcher Serie sie stammen, ist der Wuchs besonders kompakt, mittelstark oder stark. White chrysanthemums are also, of course, linked to sorrow and mourning when it comes to their meaning. Laden Sie lizenzfreie Bilder, Illustrationen, Vektorgrafiken, Clipart und Videos auf Adobe Stock für Ihre kreativen Projekte herunter. Compound RI Relative peak area percent1) DB-5 Fresh Shady-dried Freeze-dried 1 α-Pinene 873 0.4 0.2 tr 2 Dehydrosabinene 880 0.2 0.1 0.1 3 Camphene 887 1.4 0.4 0.2 4 Sabinene 919 0.3 0.1 tr albescens flowers, Codariocalyx motorius (Houtt.) Who Touched My Tail! Most species originate from East Asia and the center of diversity is in China. Ziehen Sie Ihre eigenen Herbst-Chrysanthemen heran, ist ein mineralischer Volldünger etwa ab Ende Mai ratsam. Diese Methode wendete man früher häufig an, als Herbst-Chrysanthemen noch nicht die heutige Massenware für eine Saison waren. These species were previously classified under the genus name Dendranthema. albescens, Vernonia condensata Baker (also known as Acmella ciliata (Kunth) Cass. In ihrer Heimat Ostasien war das schon zu Zeiten des Philosophen und Religionsstifters Konfuzius (551 bis 479 vor Christus) so. Niacin has a small uric acid-raising effect, which is doubtful to be of negative clinical significance.60, Good information for both patients and clinicians on the new approach to gout, Da Cheng Hao, ... Pei Gen Xiao, in Medicinal Plants, 2015. Chrysanthemum Flower (Chrysanthemum morifolium) is consumed as a tea to nourish the Yin and as an herb to remove wind and occasional heat (irritation) from several parts of the body in normal, healthy individuals. Print uden billeder. Späte Herbst-Chrysanthemen beginnen im Freiland Ende Oktober mit der Blüte. They reported that the anti-inflammatory action of luteolin has been attributed to inhibition of inducible nitric oxygen synthase (iNOS), iNOS expression, and NO production; scavenging of reactive oxygen species (ROS); inhibition of ROS production and activation of antioxidant enzymes; inhibition of leukotriene production and release; suppression of pro-inflammatory cytokine expression; inhibition of the NF-κB pathway, protein kinase B (AKT), and the mitogen-activated protein kinase (MAPK) pathway; inhibition of adhesion molecule membrane binding, hyaluronidase activity, and elastase activity; stabilization of mast cells; reduction of vascular permeability; and modulation of cell membrane fluidity. Their commercial value is largely attributed to the diversity of ornamental traits created by targeted breeding, which has been primarily focused on petal colors and the shapes of ray florets ( Flower color distribution: Bicolored. H. Ohashi, and Artemisia asiatica Nakai (also known as Artemisia dubia var. A sesquiterpene lactones (2) obtained from Chresta martii displayed excellent NF-κB inhibition with the IC50 value of 0.7 μM, equivalent to parthenolide (IC50 = 0.7 μM) used as standard drug. It is a cross-pollination species, which can reproduce both sexually by out-crossed seeds and asexually through rhizomes [6]. They are native to East Asia and northeastern Europe. It showed 96.8% inhibition compared to resveratrol 90.2% at a lowest concentration of 0.01 mM. The Chrysanthemum is a member of the Asteraceae (Compositae) family, related to dahlias, sunflowers, marigolds, zinnias, and cosmos. Inflammation occurs as a natural response to harmful stimuli, such as tissue stress, injury, and microbial invasion, to maintain homeostasis. Yin Yang Eye GunGun’s Marriage Contract. Now over 3,000 varieties have been found. It is in flower from August to October. Chrysanthemum has been used for hundreds of years in manufacturing medicine. The specific signals from the chemotaxonomically significant compounds of chromones and coumarins in S. divaricata are exhibited distinctively in the composite features of both NMR fingerprints and HPLC profiles. Flower color distribution: Marginate. Hydrophilic antioxidant capacity was evaluated using the TEAC assay, while the Folin–Ciocalteu assay with a previous cleanup was used to establish total polyphenol content. The biologically active terpenoids should be included in these approaches. A triterpene 108 was obtained from Pellacalyx saccardianus, exhibited the better COX-2 inhibition than standard drug used. Chrysanthemum is a valued ornamental flower that has been grown for more than 3,000 years. Chrysanthemum indicum is a plant of the temperate zone and a parent of the cultivated Chrysanthemums. The category of flower type depends on the arrangement of petals on the flower and the shape of the bloom, such as whether the petals are reflexed or incurved, and whether the blooms … Luteolin is considered non-toxic. Chrysanthemum indicum is a PERENNIAL growing to 0.6 m (2ft) by 0.6 m (2ft in). Bloom Size: 1"-2" Bloom Time: Mid Winter. The presence of a hydroxyl group at the 3′- position distinguishes this flavone from apigenin, which has been studied for many years. However, the relevant pharmacological bases for these indications are often absent. Chrysanthemum are herbaceous perennial plants, of which C. indicum, is one of the most widespread species ranging from the north of Russia to the southeastern part of Asia, Korea, China and Europe [5]. Der ideale Überwinterungsort ist ein kalter Frühbeetkasten oder ein ungeheiztes Gewächshaus. Sarasadat Hosseini, ... Gholamreza Karimi, in Biomedicine & Pharmacotherapy, 2018. Apocynum venetum has long been used in traditional Chinese and Uygur medicine. The species is hermaphrodite (has both male and female organs) and is pollinated by Insects. The mRNA expression of the downstream genes of Wnt pathway, beta-catenin, and c-Myc, simultaneously decreased as cell proliferation decreased and apoptosis increased [112]. Herbst-Chrysantheme Chrysanthemum Indi... Gefüllte Garten-Chrysanthemen Mix,3 Pf... Strahlen-Chrysantheme "Goldgelb",3 Pfl... Besuchen Sie die Webseite um dieses Element zu sehen. Chrysanthemum Indicum Hybriden, deren natürliche Blütezeit in die Zeit vom Spätherbst bis zum frühen Winter fällt, kann man zu jeder Jahreszeit bereits in voller Blüte kaufen. Die meisten kennen sie jedoch als Herbst-Chrysantheme. Ihren Siegeszug nach Europa trat die kaiserliche Blume und … The differences in the total and individual polyphenol content and hydrophilic antioxidant capacity of seven varieties of tomato cultivated in Vegas Bajas del Guadiana, Badajoz (Spain), were evaluated (Vallverdú-Queralt et al., 2011), which were collected from two consecutive harvests (2008–2009). Some researchers have provided non-specific or non-accepted plant names, including Chrysanthemum indicum var. Übersetzung: Herbst-Chrysantheme Extrakt. Chrysanthemum indicum is a plant of the temperate zone and a parent of the cultivated Chrysanthemums. Compounds 164 and 167 displayed almost 10 times greater 5-LOX inhibition than the zileuton at concentration of 20 μM. The active ingredients were most likely linarin and luteolin, which are found in traditional preparations used for treatment of prostatitis and chronic pelvic inflammation [29]. Dort nahm man die staudigen bis halbstrauchigen Symbolpflanzen, die für ein langes Leben stehen, früh in Gartenkultur. as accepted in http://mpns.kew.org/mpns-portal), Cymbopogon citratus (DC). Generality. Luteolin is a flavone compound present in many medicinal plants. Chrysanthemum flowering time is defined as early (September), mid (October) or late (November). 1. The anti-inflammatory activity of luteolin was comprehensively reviewed in 2008 (Seelinger et al., 2008). Chrysanthemum indicum L. (Compositae), which is widespread in Korea, is a well-known herb and medicinal plant with small yellow flowers. Sixteen SMs, belonging to the classes of cinnamoylquinic acids and flavonoids, were identified. Large incurve blooms in bronze, gold, yellow and red are extremely popular before Christmas. Unlike quercetin, however, luteolin has not been granted Generally Recognized as Safe status by the U.S. FDA. “Long-storage” tomato (Solanum lycopersicum) is traditionally cultivated under no water supply, the fruits of which combine a good taste with excellent nutritional properties. durch ihren kugeligen Wuchs sowie eine reiche Rundum-Blüte aus. The chemical structure of luteolin is shown in Fig. The Compendium of Materia Medica (Ming Dynasty, by LI Shizhen) stated that the herb eliminates dampness through diuresis. Die dunkelgrünen Blätter von Chrysanthemum indicum sind tief eingeschnitten und duften aromatisch. Chrysanthemum is a floricultural, ornamental and medicinal plant with tremendous income cash crop which is cultivated chiefly in winter. Another recommended formula mainly composed of Apocynum venetum leaves, Suosuo grape and Ci tang (a kind of sugar secreted by Alhagi pseudoalhagi Desv.) Bis heute unterscheiden sich die unter Glas herangezogenen Herbst-Chrysanthemen von den winterhärteren Garten-Chrysanthemen (Chrysanthemum x grandiflorum-Hybriden) dadurch, dass sie Frost schlechter vertragen. Betegnelsen krysantemum eller vinter­asters omfatter talrige former, der er fremkommet ved en række krydsnin­ger mellem arter og hybrider. In one research, it was illustrated that CISCFE enhanced BLM anti-tumor effect and reduced toxicity of BLM in tumor-bearing mice. Chrysanthemums are among the most famous traditional Chinese flowers and are popular around the world as cut flowers and pot plants. Fasih A. Hameed MD, ABIHM, in Integrative Medicine (Fourth Edition), 2018. Die Blütenwunder gehören zur Familie der Korbblütler (Asteraceae). Bis heute unterscheiden sich die unter Glas herangezogenen Herbst-Chrysanthemen von den winterhärteren, Anders als die oft langstieligen Garten-Chrysanthemen, auch als. Noni was found to have in vitro inhibition of xanthine oxidase,54 but no clinical trials have been performed to date. Jedes Teilstück sollte mindestens einen Trieb und Wurzeln haben. There are numerous new ethnobotanical studies of traditional antigout agents, many of which are yielding promising results and confirming the wisdom of indigenous healing systems. Der Oberboden sieht dann zwar trocken aus, doch darunter ist die Erde noch nass. The book stated that the fired leaves and tender stems of Apocynum venetum could be served as food and tea. About Mums. Several plants including those of Alpinia oxyphylla, Chrysanthemum indicum Linne (CI), and Chrysanthemum morifolium Ramat (CM) plants can reduce the production of ROS through direct activation or increasing mRNA expression of reductive enzymes such as catalase, superoxide dismutase (SOD), glutathione reductase (GR), and phase two enzyme [Nicotine-Adenine Diphosphonucleotide (NADP(H))-Quinone oxidoreductase 1 (NQO1)] [31–33]. The promoters of CDKN2A and SFRP2, as well as the upstream genes of the Wnt pathway, SFRP5 and WIF1, were demethylated, which increase the mRNA expression of some of these genes. The total flavonol content ranged between 68 and 408 mg/kg fresh weight in nine of the 10 accessions. Sixty-three volatile flavor components, which make up 89.28% of the total aroma composition of the flower oil, were tentatively characterized. Cultivation. Each bloom is made of hundreds of tiny flowers called florets. Die besten Erfolge erzielte man in klimatisch günstigen Regionen. Chrysanthemum Flower is renowned for treating different health problems. By continuing you agree to the use of cookies. Flowering month(s) September. The chrysanthemums available in the market are diverse. Herbst-Chrysanthemen (Chrysanthemum indicum) zählen zu den beliebtesten Blumen. Tomatoes, the second most important vegetable crop worldwide, are a key component in the so-called Mediterranean diet, which is strongly associated with a reduced risk of chronic degenerative diseases. This finding indicates that quercetin can be a potential inhibitor of DNA methylation. Sobald sich frisches Grün zeigt, gewöhnt man die Pflanzen an die Außenluft und pikiert sie nach etwa einer Woche. Oct 2, 2015 - Chrysanthemen Aparte Blüten im Spätherbst In China und Japan blicken Chrysanthemen auf eine mehr als 2000jährige Kulturgeschichte zurück. Numerous plants are rich in quercetin, which can inhibit both prokaryotic SssI DNMT and human DNMT1 [113]. Chang KM, Cho EM, Kim GH (2010) Chemical constituents of Chrysanthemum indicum L. flower oil and effect on osteoblastic MC3T3-E1 cells. The metabolites screened in last decade displayed moderate to excellent anti-inflammatory activities in various bioassays. Die Herbst-Chrysantheme (Chrysanthemum indicum) ist eine Pflanzenart aus der Gattung der Chrysanthemen (Chrysanthemum) innerhalb der Familie der Korbblütler (Asteraceae). Apigenin is a bioactive flavonoid from Apium graveolens L. [115] and Plantago L. [116], which are well-known traditional Chinese herbs mainly used for heat clearing and detoxifying. Zur Vermehrung teilt man die Wurzelstöcke der Chrysanthemum Indicum-Hybriden Anfang bis Ende März mit einem scharfen Messer. Their commercial value is largely attributed to the diversity of ornamental traits created by targeted breeding, which has been primarily focused on petal colors and the shapes of ray florets (Shinoyama et al., 2012 Chrysanthemum indicum: Eigenschaften und Herkunft. Die Knospen sind oft in einem tieferen Ton, sodass die Blüten beim Aufblühen durch die dunklere Mitte fast zweifarbig wirken. Flower color distribution Unicolored. Dort nahm man die staudigen bis halbstrauchigen Symbolpflanzen, die für ein langes Leben stehen, früh in Gartenkultur. Cultivation. Landraces originating from the same area exhibit different fruit morphologies but own a similar biochemical profile. Chrysanthemum indicum L. has been shown to possess antiinflammatory and anticancer activities, but its molecular targets/pathways are not yet fully understood in tumor cells. Flavonoids, which exist in numerous kinds of Chinese herbs, have extensive pharmacological activities that include anti-oxidant [101], anti-inflammatory [102], anti-tumor [103], and immunoregulation activities [104]. Chrysanthemum has been used for hundreds of years in Chinese medicine. The crop charity as nerve sedative, anti-oxidant, anti-inflammatory, anti-mutagenic, anti-microbial, anti-fungal, anti-angiogenic, anti-atherosclerosis and nematocidal goods. The active molecules in C. indicum are glycosides and flavonoids [17]. The external bracts are herbaceous, with a narrow scariety margin. PCA results show that phenolic compounds and hydrophilic antioxidant capacity were responsible for the differences among tomato samples according to variety. Leaf division: Divided/split. Rebirth of the Supreme Celestial Being. Da sie allerdings auf eine Saison ausgelegt sind, kommen sie kurzfristig auch mit schattigen Plätzen zurecht, beispielsweise im Begrüßungsarrangement an einem Hauseingang auf der Nordseite. Intensive Züchtung bietet mittlerweile eine fantastische Sortenvielfalt. The aroma constituents of Chrysanthemum indicum L. were separated by the hydro distillation extraction method using a Clevenger-type apparatus, and were analyzed by gas chromatography-mass spectrometry (GC/MS). For example, Zygophyllum simplex L. (also known as Tetraena simplex (L.) Beier & Thulin as accepted in http://mpns.kew.org/mpns-portal), Chrysanthemum indicum var. Decrease intake of sugar-containing beverages and fructose. Chrysanthemum indicum, 'Korean Hybrids' Mixed Ideal for beginners (but don't be put off if you're an expert!) “Chinese medicine categorizes herbs based on energetic properties rather than the chemical ingr… Manche Sorten erweisen sich sogar als winterhart. Die Vorratsdüngung der herangezogenen Balkonblumen reicht aus. Increase intake of omega-3 fatty acids or take a supplement. Chrysanthemum indicum (CHYIN) ... China, Himalayas, Japan, Korea, Indochina. Photo about Chrysanthemum indicum Linn flowers. Jede Qualitäts-Blumenerde bietet Chrysanthemum indicum beste Bedingungen. Quick Transmigration. Chrysanthemen (Chrysanthemum) gehören zu den populärsten Garten- und Balkonpflanzen und die Auswahl der im Handel erhältlichen Sorten ist groß, Es gibt sie mit ein- und mehrfarbigen, gefüllten und ungefüllten Blüten. Luteolin is present in vegetables, fruits, and medicinal herbs, including broccoli, onion leaves, carrots, peppers, cabbages, apple skins, Chrysanthemum indicum var. Die Vorratsdüngung der herangezogenen Balkonblumen reicht aus. Inflorescence Capitulum (head) Leaf division Pinnately lobed. Quantitative analyses were performed to monitor the changes in the phenolic content along the batch. It also ensures the safe and effective use of clinical medicine. Nur Aziz, ... Jae Youl Cho, in Journal of Ethnopharmacology, 2018. Die Art Chrysanthemum indicum ist unter vielen Namen bekannt. Volatile Flavor Composition of Chrysanthemum indicum Flower 321 Table 1. Chrysanthemum has been used for hundreds of years in manufacturing medicine. Flavonoids, particularly luteolin, are derived from a variety of plants with traditional uses that have long been studied for their anti-inflammatory activity. Volatile flavor components identified in the gamguk essential oils No. Moreover, because luteolin exhibits anti-inflammatory activity at micromolar concentrations (Seelinger et al., 2008), it has emerged as a potentially promising compound for further development. Flower, secondary color(s): White-RHS NN155B. Prüfen Sie daher vor dem Gießen, ob die Pflanze wirklich schon wieder Wasser braucht. Wichtig ist es, die Überwinterungsräume bei jeder Gelegenheit zu lüften. Chen … Quick Transmigration. Each bloom is made of hundreds of tiny flowers called florets. Growing Requirements of Chrysanthemum Plants: Chrysanthemums grow best and produce the most flowers if they are planted in full sunshine. The medicinal use of Cannabis is increasing as countries worldwide are setting up official programs to provide patients with access to safe sources of medicinal-grade Cannabis. Apigenin is a newly reported plant-derived HDAC inhibitor. The flavones are a class of flavonoids, some of the most abundant secondary metabolites in plants, and are widely known to be responsible for various pharmacological activities. Increase intake of low-fat dairy, up to two servings per day. Chrysanthemum indicum, or Ye Ju Hua, and Chrysanthemum moriflorum, Ju Hua, have a long history for the treatment of inflammation, hypertension, and respiratory diseases in traditional Chinese and Korean medicine. Im alten China waren sie das Symbol des Herbstes und eines langen Lebens. J. D. Yang is an expert in Chinese and integrative medicine and founder of Tao Integrative. Or Chrysanthemum morifolium Ramat flowers in plantation. The tea products have different formulations, including tea bags, powder, and crimped and curled roasted leaves. Photo Chrysanthemum (Indicum Grp) Bonbini on Group Flowers. Interstellar. Compound 185 showed the more selectivity towards COX-2 than indomethacin. Chrysanthemum indicum (Indian chrysanthemum ) will reach a height of 0.6m and a spread of 0.6m after 1-2 years.. Learn more about fresh cut single headed Chrysanthemum Blooms here. Chrysanthemum (Indicum Grp) Belgian Mums Staviski Dark Pink. Image of cultivate, blossoming, freshness - 121727288 Befriending the Most Powerful Person. Consider drinking coffee, one to two cups a day. Flower color Purple-UPOV Violet-RHS N080B. Once a symbol of Japanese royalty, the chrysanthemum plant has been prized for its beautiful flowers for centuries. Best grown in fertile, moist or moist but well-drained soil in full sun. View abstract. Flower type: Single. However, further study is needed to confirm this hypothesis. By significantly inhibiting HDAC activity, apigenin increased global histone acetylation, promoted hyperacetylated histone H3 localization on the p21(WAF1/CIP1) promoter, caused cell cycle G2/M arrest and apoptosis, and increased p21(WAF1/CIP1) level and p21(WAF1/CIP1)-PCNA (proliferating cell nuclear antigen) interaction both in MDA-MB-231 breast cancer [118] and human prostate cancer cells [119]. … We previously found that luteolin acts partly by preventing adenosine triphosphate (ATP) from binding to spleen tyrosine kinase (Syk) or proto-oncogene tyrosine-protein kinase (Src) and confirmed that mechanism of action using a docking analysis (Lee et al., 2015a, 2015b). Encourage weight loss and maintenance of a healthy body mass index. Flower type Semi-double . Cottage/Informal, Beds and borders, Flower Arranging. Activation of HO-1 results in increased levels of antioxidant substrates such as biliverdin, bilirubin, and ferritin [38]. Meist verschwinden sie unter dem Blütenbesatz. ANXIOLYTIC EFFECT OF ETHANOLIC EXTRACT OF FLOWERS OF CHRYSANTHEMUM INDICUM IN ALBINO MICE. Inflorescence: Raceme. High luteolin content has also been reported in parsley, thyme, peppermint, basil, celery, and artichoke (Jeong et al., 2014; Kim et al., 2014a, 2014b; Li et al., 2012; Pandurangan and Esa, 2014; Wall et al., 2013; Yang et al., 2017). Chrysanthemum indicum L. has been shown to possess antiinflammatory and anticancer activities, but its molecular targets/pathways are not yet fully understood in tumor cells. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/B9780128138328000042, URL: https://www.sciencedirect.com/science/article/pii/B9780124058859000218, URL: https://www.sciencedirect.com/science/article/pii/B9780323358682000694, URL: https://www.sciencedirect.com/science/article/pii/B9780081000854000013, URL: https://www.sciencedirect.com/science/article/pii/S0753332218346158, URL: https://www.sciencedirect.com/science/article/pii/S0753332216317668, URL: https://www.sciencedirect.com/science/article/pii/S0223523419305628, URL: https://www.sciencedirect.com/science/article/pii/S0378874117334578, URL: https://www.sciencedirect.com/science/article/pii/S0378874112000712, URL: https://www.sciencedirect.com/science/article/pii/S1043661816305254, Herbal Chrysanthemi Flos, Oxidative Damage and Protection against Diabetic Complications, Diabetes: Oxidative Stress and Dietary Antioxidants, Effects of plant extracts and bioactive compounds on attenuation of bleomycin-induced pulmonary fibrosis, Sarasadat Hosseini, ... Gholamreza Karimi, in, Neuroprotective mechanisms of plant extracts against MPTP induced neurotoxicity: Future applications in Parkinson’s disease, Abdelrahman Ibrahim Abushouk, ... Mohamed M. Abdel-Daim, in, Human disorders associated with inflammation and the evolving role of natural products to overcome, Navneet Kishore, ... Akhilesh Kumar Verma, in, Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies, Jeong et al., 2014; Kim et al., 2014a, 2014b; Li et al., 2012; Pandurangan and Esa, 2014; Wall et al., 2013; Yang et al., 2017, Farzaei et al., 2013; Ferrari et al., 2013; Ramezani et al., 2009, Original paper used non-validated names that are not listed in, Botany, traditional uses, phytochemistry and pharmacology of Apocynum venetum L. (Luobuma): A review, Epigenetic regulation of active Chinese herbal components for cancer prevention and treatment: A follow-up review, Flowering aerial parts (Jeddah, Saudi Arabia), Methanol at room temperature, followed by fractionation, Luteolin− 7-O-β-D-glucoside, one of five major phenolic compounds isolated, showed antioxidant and anti-inflammatory activity at 1, 10, and 100 μM (, Provided by Amore Pacific Corporation (Seoul, Korea), Suppressed the inflammatory response in macrophages, particularly at 200 and 300 μg/ml (, Anti-inflammatory, analgesic, and hepatoprotective effects, Maceration with ethanol 96%, followed by liquid/liquid partition with organic solvent to obtain hexane, dichloromethane, and ethyl acetate partitions, Ethyl acetate partition (EAP) 50, 100, 200 mg/kg (, Pre-treatment with EAP at all doses prevented liver damage in rats (, Southeast Asia, Africa, and Latin America, Erythema, edema, hyperplasia, skin photoaging, and photocarcinogenesis, Leaves acquired from ERVITAL (Mezio, Castro Daire, Portugal), Lipid- and essential oil-free infusion, followed by fractionation, Oil/water emulsion containing 4% (w/w) extract, 1% (w/w) extract, and 1% polyphenol-enriched fraction containing flavonoids fraction 0.66% (w/w) + tannins fraction 0.34% (w/w), Australia, India, China, Japan, and Korea, Infectious diseases, pain, inflammatory diseases, Leaves (local herbal market in southern Korea), 70% methanol for 2 weeks at room temperature, Exhibited anti-inflammatory activity in ear edema model in ICR mice, shown by reduced ear thickness and improved histopathological change during ear inflammation (, Aerial parts (Popa Mountain National Park, Mandalay, Myanmar), Exerted anti-inflammatory activity mediated by suppression of NO and PGE, Thailand, Malaysia, India, Southern China, Sri Lanka, and Vietnam, Asthma, fever, cough, vomiting, and skin diseases, Aerial parts obtained from Ayurved Siriraj Manufacturing Unit of Herbal Medicines and Products (CATTM), Faculty of Medicine Siriraj Hospital (Mahidol University, Thailand), Maceration with 80% ethanol, followed by fractionation, Polyphenolic compounds in the extract were identified and quantified, and one contained luteolin, 95% ethanol extract purchased from Plant Extract Bank of the Plant Diversity Research Center (Daejeon, Korea), 0.78, 1.56, 3.12, 6.25, 12.5, 25, 50, and 100 μg/ml (, Bruising, pain, rheumatism, insect bites, and inflammatory diseases, Ethanol at room temperature, followed by fractionation, Paw swelling reduced by LTE and LTA (both at 125 and 250 mg/kg) and luteolin (25 mg/kg) in monosodium urate crystal-induced inflammation in albino Swiss mice (, Rhizomes from Thai traditional drug store (Songkhla, Thailand), Maceration with ethanol at room temperature, followed by fractionation, Dyspepsia, heartburn, spleen/liver disorders, arthritis, and rheumatic diseases, Leaves obtained from Min-Dle-Leh-Food (Uiryeong, Korea), Methanol and heated at 85 °C for 4 h to obtain, TOME and TOWE suppressed NO production with an IC, 600 mg/kg extracts for carrageenan-induced paw edema in guinea pigs (, Methanol and hexane extracts showed topic and, Inflammatory diseases of the gastrointestinal tract, Inflorescences (Fraiburgo, Santa Catarina, Brazil), Macerated with 70% (v/v) aqueous ethanol at room temperature for 7 days, followed by filtration and solvent evaporation to obtain hydroalcoholic extract of inflorescence of, HEAS ameliorated pathological changes in dextran sulfate sodium–induced colitis in Swiss mice (at 10 and 100 mg/kg); dose-dependent attenuation of NO production by HEAS up to 50% at 100 mg/ml in LPS-induced NO production in rat peritoneal macrophages. 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